Templated assembly of albumin-based nanoparticles for simultaneous gene silencing and magnetic resonance imaging.

Supporting Information Templated assembly of albumin-based nanoparticles for simultaneous gene silencing and magnetic resonance imaging

ANALYTICAL STUDY OF EFFECT OF BILAYER INORGANIC AND ORGANIC COATING AROUND THE IRON OXIDE NANOPARTICLES ON MAGNETIC RESONANCE IMAGING CONTRAST

Background & Aims: In recent years, iron oxide nanoparticles have been used in contrast-enhanced magnetic resonance imaging for diagnosing a wide range of diseases. In order to provide biocompatibility and prevent the toxicity of the nanoparticles, using organic or inorganic coating around these nanoparticles is important for their application. The aim of this study is to investigate the effect...

Size Reproducibility of Gadolinium Oxide Based Nanomagnetic Particles for Cellular Magnetic Resonance Imaging: Effects of Functionalization, Chemisorption and Reaction Conditions

We developed biofunctionalized nanoparticles with magnetic properties by immobalizing diethyle-neglycol (DEG) on Gd2O3, and PEGilation of small particulate gadolinium oxide (SPGO) with two me-thoxy-polyethyleneglycol-silane (mPEG-Silane 550 and 2000 Da) using a new supervised polyol route, described recently. In conjunction to the previous study to achieve a high quality synthesis and increase ...

Size Reproducibility of Gadolinium Oxide Based Nanomagnetic Particles for Cellular Magnetic Resonance Imaging: Effects of Functionalization, Chemisorption and Reaction Conditions

We developed biofunctionalized nanoparticles with magnetic properties by immobalizing diethyle-neglycol (DEG) on Gd2O3, and PEGilation of small particulate gadolinium oxide (SPGO) with two me-thoxy-polyethyleneglycol-silane (mPEG-Silane 550 and 2000 Da) using a new supervised polyol route, described recently. In conjunction to the previous study to achieve a high quality synthesis and increase ...

Theranostic nanoparticles based on bioreducible polyethylenimine-coated iron oxide for reduction-responsive gene delivery and magnetic resonance imaging

Theranostic nanoparticles based on superparamagnetic iron oxide (SPIO) have a great promise for tumor diagnosis and gene therapy. However, the availability of theranostic nanoparticles with efficient gene transfection and minimal toxicity remains a big challenge. In this study, we construct an intelligent SPIO-based nanoparticle comprising a SPIO inner core and a disulfide-containing polyethyle...